AQP10 rabbit pAb

AQP10 rabbit pAb

AO-06-ES9400-50

AQP10 rabbit pAb 50μL

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Antibody Product Overview

ELK.NoES9400
Product nameAQP10 rabbit pAb
ReactivityHuman;Rat;Mouse;
ApplicationsWB;ELISA
Other name
Size50μL
Unit price ($)148
Human gene ID89872
Human Swiss-ProtQ96PS8
SourceRabbit
IsotypeIgG
TargetAQP10
Fields
Gene nameAQP10
Protein nameAquaporin-10 (AQP-10) (Aquaglyceroporin-10) (Small intestine aquaporin)
Human gene link
Human Swiss linkView Human Swiss-Prot
Mouse gene ID
Mouse gene link
Mouse Swiss-Prot
Mouse Swiss link
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from human protein . at AA range: 230-310
SpecificityAQP10 Polyclonal Antibody detects endogenous levels of protein.
FormulationLiquid in PBS containing 50% glycerol, and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000 ELISA 1:5000-20000
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)33kD
BackgroundThis gene encodes a member of the aquaglyceroporin family of integral membrane proteins. Members of this family function as water-permeable channels in the epithelia of organs that absorb and excrete water. This protein was shown to function as a water-selective channel, and could also permeate neutral solutes such as glycerol and urea. [provided by RefSeq, Jul 2008],
Functiondomain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water channel. Not permeable to urea and glycerol. May contribute to water transport in the upper portion of small intestine.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,tissue specificity:Expressed exclusively in duodenum and jejunum. Highest expression in absorptive epithelial cells at the tips of villi in the jejunum.,
Subcellular locationApical cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Lipid droplet . Detected around lipid droplets. .
ExpressionDetected in epithelial cells on villi in the ileum, and also in stomach, jejunum, colon, rectum, white adipose tissue and placenta (at protein level) (PubMed:15221416, PubMed:23382902). Expressed in duodenum and jejunum. Highest expression in absorptive epithelial cells at the tips of villi in the jejunum (PubMed:11573934, PubMed:12084581). Detected in subcutaneous adipose tissue (PubMed:23382902).

Additional Images

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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES9400-50
: 10 Produits
Hurry! only 10 items left in stock.

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