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Antibody Product Overview
| ELK.No | ES9460 |
| Product name | CANB1 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 5534 |
| Human Swiss-Prot | P63098 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CANB1 |
| Fields | >>MAPK signaling pathway;>>Calcium signaling pathway;>>cGMP-PKG signaling pathway;>>Oocyte meiosis;>>Cellular senescence;>>Wnt signaling pathway;>>Axon guidance;>>VEGF signaling pathway;>>Osteoclast differentiation;>>C-type lectin receptor signaling pathway;>>Natural killer cell mediated cytotoxicity;>>Th1 and Th2 cell differentiation;>>Th17 cell differentiation;>>T cell receptor signaling pathway;>>B cell receptor signaling pathway;>>Long-term potentiation;>>Glutamatergic synapse;>>Oxytocin signaling pathway;>>Glucagon signaling pathway;>>Renin secretion;>>Alzheimer disease;>>Amyotrophic lateral sclerosis;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Amphetamine addiction;>>Tuberculosis;>>Human cytomegalovirus infection;>>Human T-cell leukemia virus 1 infection;>>Kaposi sarcoma-associated herpesvirus infection;>>Human immunodeficiency virus 1 infection;>>PD-L1 expression and PD-1 checkpoint pathway in cancer;>>Lipid and atherosclerosis |
| Gene name | PPP3R1 CNA2 CNB |
| Protein name | Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q63810 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P63100 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | CANB1 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 18kD |
| Background | function:Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.,miscellaneous:This protein has four functional calcium-binding sites.,similarity:Belongs to the calcineurin regulatory subunit family.,similarity:Contains 4 EF-hand domains.,subunit:Composed of a catalytic subunit (A) and a regulatory subunit (B)., |
| Function | function:Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.,miscellaneous:This protein has four functional calcium-binding sites.,similarity:Belongs to the calcineurin regulatory subunit family.,similarity:Contains 4 EF-hand domains.,subunit:Composed of a catalytic subunit (A) and a regulatory subunit (B)., |
| Subcellular location | Cytoplasm, cytosol . Cell membrane . Cell membrane, sarcolemma . Cell membrane ; Lipid-anchor . Translocates from the cytosol to the sarcolemma in a CIB1-dependent manner during cardiomyocyte hypertrophy. . |
| Expression | Blood,Fetal brain cortex, |
Additional Images
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Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES9460-50
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