CTAG2 rabbit pAb

CTAG2 rabbit pAb

AO-06-ES9490-50

CTAG2 rabbit pAb 50μL

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Antibody Product Overview

ELK.NoES9490
Product nameCTAG2 rabbit pAb
ReactivityHuman;Rat;Mouse;
ApplicationsWB;ELISA
Other name
Size50μL
Unit price ($)148
Human gene ID30848
Human Swiss-ProtO75638
SourceRabbit
IsotypeIgG
TargetCTAG2
Fields
Gene nameCTAG2 ESO2 LAGE1
Protein nameCancer/testis antigen 2 (CT2) (Autoimmunogenic cancer/testis antigen NY-ESO-2) (Cancer/testis antigen 6.2) (CT6.2) (L antigen family member 1) (LAGE-1)
Human gene link
Human Swiss linkView Human Swiss-Prot
Mouse gene ID
Mouse gene link
Mouse Swiss-Prot
Mouse Swiss link
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityCTAG2 Polyclonal Antibody detects endogenous levels of protein.
FormulationLiquid in PBS containing 50% glycerol, and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000 ELISA 1:5000-20000
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)23kD
BackgroundThis gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
Functiondomain:A transmembrane domain is present in isoform LAGE-1A.,similarity:Belongs to the CTAG family.,tissue specificity:Testis and very low level in placenta and in some uterus samples. Observed in 25-50% of tumor samples of melanomas, non-small-cell lung carcinomas, bladder, prostate and head and neck cancers.,
Subcellular locationcentrosome,
ExpressionTestis and very low level in placenta and in some uterus samples. Observed in 25-50% of tumor samples of melanomas, non-small-cell lung carcinomas, bladder, prostate and head and neck cancers.

Additional Images

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Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES9490-50
: 10 Produits
Hurry! only 10 items left in stock.

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