PSF2 rabbit pAb

PSF2 rabbit pAb

AO-06-ES9595-100

PSF2 rabbit pAb 100μL

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Antibody Product Overview

ELK.NoES9595
Product namePSF2 rabbit pAb
ReactivityHuman;Mouse
ApplicationsWB;ELISA
Other name
Size100μL
Unit price ($)248
Human gene ID51659
Human Swiss-ProtQ9Y248
SourceRabbit
IsotypeIgG
TargetPSF2
Fields
Gene nameGINS2 PSF2 CGI-122 DC5 HSPC037
Protein nameDNA replication complex GINS protein PSF2 (GINS complex subunit 2)
Human gene link
Human Swiss linkView Human Swiss-Prot
Mouse gene ID
Mouse gene link
Mouse Swiss-ProtQ9D600
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityPSF2 Polyclonal Antibody detects endogenous levels of protein.
FormulationLiquid in PBS containing 50% glycerol, and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000 ELISA 1:5000-20000
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)20kD
BackgroundThe yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008],
Functionfunction:The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.,mass spectrometry:This is the measured mass for the GINS complex PubMed:17557111,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the GINS2/PSF2 family.,subunit:Component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4. Forms a stable subcomplex with GINS3. GINS complex interacts with DNA primase in vitro.,
Subcellular locationNucleus . Chromosome . Associates with chromatin. .
ExpressionBrain,Dendritic cell,Umbilical cord blood,

Additional Images

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Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES9595-100
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Hurry! only 10 items left in stock.

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