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Antibody Product Overview
| ELK.No | ES9910 |
| Product name | NGDN rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 25983 |
| Human Swiss-Prot | Q8NEJ9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | NGDN |
| Fields | |
| Gene name | NGDN C14orf120 |
| Protein name | Neuroguidin (EIF4E-binding protein) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9DB96 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 240-320 |
| Specificity | NGDN Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 34kD |
| Background | Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar 2008], |
| Function | function:Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs.,similarity:Belongs to the SAS10 family.,subcellular location:Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites.,subunit:Interacts with CPEB1 and EIF4E., |
| Subcellular location | Nucleus . Nucleus, nucleolus . Chromosome, centromere . Cytoplasm . Cell projection, axon . Cell projection, dendrite . Cell projection, filopodium . Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites (By similarity). Translocated from nucleolus to nuclear foci in response to UV damage. . |
| Expression | Brain,Epithelium,Placenta, |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES9910-100
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