Product Information
|
Protein full name |
Napsin-A |
|
Synonyms |
Asp 4, ASP4, Aspartyl protease 4, KAP, Kdap, NAP1, NAPA, NAPSA, Napsin 1, Napsin A, napsin A aspartic peptidase, Pronapsin A, SNAPA, TA01/TA02, napsin A aspartic peptidase |
|
Uniprot ID |
O96009 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human NAPSIN-A |
|
Isotype |
IgG1, κ |
|
Clone Number |
SB137 |
|
Predicted MW./Observed MW. |
45 kDa / 35-50 kDa |
|
Purity |
Affinity purification |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 1000-1: 2000 | Neuiofilament heavy polypeptide |
Background
Napsin A is an aspartic proteinase that is expressed in normal lung and kidney. In the lung, napsin A is expressed by type II pneumocytes and alveolar macrophages, where it plays a role in processing surfactant protein B. Napsin A is expressed in lung adenocarcinomas, where it can be used to identify primary and metastatic lesions with greater sensitivity compared to TTF-1. Napsin A expression has also been described in other types of cancer, such as kidney and thyroid cancer.
Images
|
|
WB analysis of NAPSIN A(GB151010). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 1000, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (GB23301), 1: 5000, RT, 1h. |
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.