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Product Information
|
Protein full name |
Beta-2-microglobulin |
|
Synonyms |
Beta-2-microglobulin form pI 5.3, B2M, CDABP0092, HDCMA22P, B2m, Hdcma22p, Beta chain of mhc class 1 proteins, IMD43 |
|
Uniprot ID |
P01887 |
|
Immunogen |
Recombinant protein corresponding to Mouse beta 2 Microglobulin |
|
Isotype |
IgG |
|
Predicted MW./Observed MW. |
14 kDa / 14 kDa |
|
Purity |
Affinity purification |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human | 1: 500-1: 1000 | Jurkat, HepG2, Raji |
Background
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.
Images
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WB analysis of beta 2 Microglobulin(GB111119). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 500, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h. |
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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