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Product Information
|
Protein full name |
Urokinase-type plasminogen activator |
|
Synonyms |
U-plasminogen activator, Plau, ATF, URK, uPA, Urinary, Urokinase |
|
Uniprot ID |
P06869 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse uPA |
|
Isotype |
IgG |
|
Predicted MW./Observed MW. |
48 kDa / 48 kDa |
|
Purity |
Affinity purification |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse | 1: 500-1: 1000 | prostate |
Background
PLAU, a member of the peptidase family S1, is a potent plasminogen activator and is clinically used for therapy of thrombolytic disorders. PLAU specifically cleaves the Arg-|-Val bond in plasminogen to form plasmin uPA is a potent marker of invasion and metastasis in a variety of human cancers associated with breast, stomach, colon, bladder, ovary, brain and endometrium . The protein is found in high and low molecular mass forms.
Images
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WB analysis of uPA(GB11958). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 500, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h. |
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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