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Product Information
|
Protein full name |
Disintegrin and metalloproteinase domain-containing protein 10 |
|
Synonyms |
AD10, AD18, CD156c, HsT18717, MADM, RAK, kuz, CDw15 |
|
Uniprot ID |
O35598 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse ADAM10 |
|
Isotype |
IgG |
|
Predicted MW./Observed MW. |
84 kDa / 60-70 (mature)/90-100 (precursor ) kDa |
|
Purity |
Affinity purification |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, lung |
Background
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing.
Images
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WB analysis of ADAM10(GB11318). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 500, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h. |
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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