Product InformationDescriptionBMP4 rabbit polyclonalProtein full nameBone morphogenetic protein 4SynonymsBMP4, BMP2B, BMP2B1, MCOPS6, OFC11, ZYME, bone morphogenetic protein 4ImmunogenRecombinant p
Product Information
Protein full name | Bone morphogenetic protein 4 |
Synonyms | BMP4, BMP2B, BMP2B1, MCOPS6, OFC11, ZYME, bone morphogenetic protein 4, ZYME, zbmp-4, DVR4 |
Uniprot ID | P21275 |
Immunogen | Recombinant protein corresponding to Mouse Mouse BMP4. |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Secreted |
Applications
| Applications | Species | Dilution | Positive Tissue |
| IHC/IF | Mouse | 1: 1000-1: 4000 | bone |
Background
BMP4 is a polypeptide belonging to the TGF-βsuperfamily of proteins, which binds to 2 different types of serine-threonine kinase receptors known as BMPR1 and BMPR2. Signal transduction via these receptors occurs via Smad and map kinase pathways to effect transcription of its target genes. Like other bone morphogenetic proteins, it is involved in bone and cartilage development, specifically tooth and limb development and fracture repair, playing an important role in the onset of endochondral bone formation in humans. It has been shown to be involved in muscle development, bone mineralization, and ureteric bud development.
Images
| IHC analysis of BMP4(GB11520). Sample: Mouse bone, 4% PFA (G1101) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98°C, 20 min. Primary antibody: 1: 2000, 4°C overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h. |
| IHC analysis of BMP4(GB11520). Sample: Mouse bone, 4% PFA (G1101) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98°C, 20 min. Primary antibody: 1: 2000, 4°C overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 µg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
Datasheet: Download datasheet 1
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