Product Information
Protein full name | Mimecan |
Synonyms | Osteoglycin, Ogn, Og, Osteoinductive factor, SLRR3A, OIF |
Uniprot ID | Q62000 |
Immunogen | Recombinant protein corresponding to Mouse OIF |
Isotype | IgG |
Predicted MW./Observed MW. | 34 kDa / 34 kDa |
Purity | Affinity purification |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Mouse, Rat | 1: 500-1: 1000 | heart, liver, kidney |
Background
Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta. Mimecan is a small proteoglycan which contains tandem leucine-rich repeats. Mimecan is encoded by the OGN gene, a member of the small leucine-rich proteoglycan (SLRP) family of proteins. Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta (TGF-beta-1 or TGF-beta-2) and may regulate osteoblast differentiation. High expression of mimecan protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants of mimecan.
Images
| WB analysis of OIF(GB111845). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 500, 4°C overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 µg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
Datasheet: Download datasheet 1
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