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Antibody Product Overview
| ELK.No | EM1041 |
| Product name | Bcl-2 Mouse mAb |
| Reactivity | Human, Rat, Mouse |
| Applications | WB, IHC, IF |
| Other name | B-Cell Leukemia/Lymphoma 2 ;B-Cell CLL/Lymphoma 2 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 596 |
| Human Swiss-Prot | P10415 |
| Source | Mouse |
| Isotype | IgG1 |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthetic Peptide |
| Specificity | |
| Formulation | |
| Clonality | Monoclonal |
| Dilution | WB 1:1,000-2,000 IHC 1:200 IF 1:100-200 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 26kDa |
| Background | BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability. |
| Function | |
| Subcellular location | Mitochondrion outer membrane,Nucleus membrane,Endoplasmic reticulum membrane |
| Expression |
Additional Images
Western blot analysis of Hela with Bcl-2 mouse mAb(6B5) diluted at 1:1,000.
IHC staining of Human tonsil tissue paraffin-embedded with Bcl-2 mouse mAb（6B5）diluted at 1:200.
Western blot analysis of 3T3 with Bcl-2 mouse mAb(6B5) diluted at 1:1,000.
IF analysis of Hela with EM1041(Left) and DAPI (Right) diluted at 1:100.
: EM1041-50
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