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Antibody Product Overview
| ELK.No | EM1058 |
| Product name | Myosin Heavy Chain Mouse mAb |
| Reactivity | Human, Mouse, Rat, Fruit Fly, Nematode |
| Applications | IHC, IF |
| Other name | Bsh, CG17927, Dm II, Dmel\CG17927, DmMHC, DROMHC, DroMII, FBgn0002741, Ifm(2)2, l(2)36Ae, l(2)k10423, l(2)M66, Mhc, Mhc36B, mMHC, MRP, Myo, Myosin heavy chain, Nup, Sht, sMHC, Stp |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 4619 |
| Human Swiss-Prot | P12882 |
| Source | Mouse |
| Isotype | IgG1 |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthetic Peptide |
| Specificity | |
| Formulation | |
| Clonality | Monoclonal |
| Dilution | IHC 1:200 IF 1:100 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 220kDa |
| Background | Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Cardiac MHC exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. These two isoforms are expressed in different amounts in the human heart. During normal physiology, beta-cardiac MHC is the predominant form, with the alpha-isoform contributing around only 7% of the total MHC. Mutations of the MHC genes are associated with several different dilated and hypertrophic cardiomyopathies. |
| Function | |
| Subcellular location | Cytoplasm, Thick filament |
| Expression |
Additional Images
Immunofluorescence Staining of nematode tissue with MYH mouse mAb(11C2) diluted at 1:100. (Provide by Tsinghua University).
Immunofluorescence double Staining of fruit fly tissue with MYH mouse mAb(11C2)(Green) and F-actin mouse mAb(red) (Provide by NIBS).
: EM1058-100
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