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Antibody Product Overview
| ELK.No | EM1059 |
| Product name | GFAP Mouse mAb |
| Reactivity | Rat, Mouse |
| Applications | WB, IHC |
| Other name | Glial Fibrillary Acidic Protein ;Intermediate Filament Protein |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 2670 |
| Human Swiss-Prot | P14136 |
| Source | Mouse |
| Isotype | IgG1 |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthetic Peptide |
| Specificity | |
| Formulation | |
| Clonality | Monoclonal |
| Dilution | WB 1:2,000-5,000 IHC 1:200-500 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 45kDa |
| Background | GFAP is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. |
| Function | |
| Subcellular location | Cytoplasm. Associated with intermediate filaments |
| Expression |
Additional Images
Western blot analysis of Rat Brain Tissue with GFAP mAb diluted at 1:5,000.
Western blot analysis of Mouse Brain Tissue with GFAP mAb diluted at 1:2,000.
Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using GFAP（EM1059）Mouse mAb diluted at 1:500.
: EM1059-50
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