| ELK.No | EM1079 |
| Product name | ErbB-2/HER-2 Mouse mAb |
| Reactivity | Human |
| Applications | WB, IHC |
| Other name | CD340, HER 2/neu, HER2, MLN 19, MLN19, NEU, NGL, p185, p185erbB2, Proto oncogene c ErbB 2, Proto oncogene Neu, TKR1 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 2064 |
| Human Swiss-Prot | P04626 |
| Source | Mouse |
| Isotype | IgG1 |
| Target | |
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| Immunogen | Synthetic Peptide |
| Specificity | |
| Formulation | |
| Clonality | Monoclonal |
| Dilution | WB 1:1,000 IHC 1:200-500 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 138kDa |
| Background | ErbB 2 is a receptor tyrosine kinase of the ErbB 2 family. It is closely related instructure to the epidermal growth factor receptor. ErbB 2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis. |
| Function | |
| Subcellular location | Cytoplasm. Nucleus and Cell membrane |
| Expression |


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