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Antibody Product Overview
| ELK.No | EM1315 |
| Product name | Smad3 (4C9) Mouse mAb |
| Reactivity | Human, Rat, Mouse |
| Applications | WB, IHC |
| Other name | hMAD3 antibody, HSPC193 antibody, LDS1C antibody, MADH3 antibody, JV15 2 antibody |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 4088 |
| Human Swiss-Prot | P84022 |
| Source | Mouse |
| Isotype | IgG1 |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthetic Peptide |
| Specificity | |
| Formulation | |
| Clonality | Monoclonal |
| Dilution | WB 1:1,000-2,000 IHC 1:100-200 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 52kDa |
| Background | Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. |
| Function | |
| Subcellular location | Cytoplasm, Nucleus |
| Expression |
Additional Images
Western blot analysis of 1) Mouse Brain Tissue Lysate, 2) Rat Brain Tissue Lysate using Smad3（ EM1315）Mouse mAb diluted at 1:2000.
Immunohistochemical analysis of paraffin-embedded Human Liver Carcinoma Tissue using Smad3（EM1315）Mouse mAb diluted at 1:200.
Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using Smad3（EM1315）Mouse mAb diluted at 1:200.
: EM1315-50
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