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Antibody Product Overview
| ELK.No | EM1326 |
| Product name | ERK1/2 (1H4) Mouse mAb |
| Reactivity | Human, Rat, Mouse |
| Applications | WB, IHC |
| Other name | MAPK, Mitogen-activated protein Kinase, PRKM2,MK01 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 5594/5595 |
| Human Swiss-Prot | P27361/P28482 |
| Source | Mouse |
| Isotype | IgG1 |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthetic Peptide |
| Specificity | |
| Formulation | |
| Clonality | Monoclonal |
| Dilution | WB 1:1,000-2,000 IHC 1:100-200 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 44,42kDa |
| Background | Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer. |
| Function | |
| Subcellular location | Nucleus |
| Expression |
Additional Images
Western blot analysis of 1) Hela Cell Lysate, 2)Mouse Brain Tissue Lysate, 3) Rat Brain Tissue Lysate using ERK1/2（EM1326）Mouse mAb diluted at 1:2000.
Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma Tissue using ERK1/2（EM1326）Mouse mAb diluted at 1:200.
Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using ERK1/2（EM1326）Mouse mAb diluted at 1:200.
: EM1326-50
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