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Antibody Product Overview
| ELK.No | EM1373 |
| Product name | NBR1 (7C3) Mouse mAb |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Other name | 1A13B, MIG19, Nbr1 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 4077 |
| Human Swiss-Prot | Q14596 |
| Source | Mouse |
| Isotype | IgG1 |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Recombinant Protein |
| Specificity | |
| Formulation | |
| Clonality | Monoclonal |
| Dilution | IHC 1:100-200 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 120kDa |
| Background | NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62. |
| Function | |
| Subcellular location | Cytoplasm, Cytoplasmic vesicle, Lysosome |
| Expression |
Additional Images
Immunohistochemical analysis of paraffin-embedded Human Skeletal Muscle Tissue using NBR1 （EM1373）Mouse mAb diluted at 1:200.
: EM1373-50
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