Recombinant Anti-MyD88 antibody (Rabbit mAb) - 50 µL

Product Information

Protein full name

Myeloid differentiation primary response protein MyD88

Synonyms

MYD88, MYD88D, mutant myeloid differentiation primary response 88, myeloid differentiation primary response gene (88)

Immunogen

Recombinant protein corresponding to Rat MYD88

Uniprot ID

Q6Y1S1

Isotype

IgG

Clone Number

SB557

Purity

Affinity purification

Predicted MW./Observed MW.

33 kDa / 33 kDa

Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 1000-1: 2000

Raji, NIH3T3, PC-3

Storage

Storage

Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Storage Buffer

PBS with 0.15% ProClin300, 100 µg/mL BSA and 50% glycerol.

background

MYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS, which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis.

Images

WB analysis of MyD88(GB15269).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 1000, 4°C overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.