Anti-c-Rel Rabbit pAb - 50 µL

Anti-c-Rel Rabbit pAb - 50 µL

Antibodies-Oncology
AO-03-GB115433-50
  • Specification: 50 µL
  • Applications: WB
  • Species: H
  • Dilution: 1: 300-1: 800
  • Positive tissue: Jurkat
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299,00 €
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Product Information

Protein full name

Proto-oncogene c-Rel

Synonyms

C Rel, Proto oncogene c Rel, REL, Oncogene REL, Avian reticuloendotheliosis

Uniprot ID

P15307

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Rel

Isotype

IgG

Predicted MW./Observed MW.

65 kDa / 65 kDa

Purity

Affinity purification

Applications

ApplicationsSpeciesDilutionPositive Tissue
WBHuman1: 300-1: 800Jurkat

Background

Proto-oncogene that may play a role in differentiation and lymphopoiesis. NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.

Images

01IKX0f2qudSZ42.jpg

 WB analysis of c-Rel(GB115433).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 800, 4°C overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.

Storage

Storage Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 µg/mL BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

Datasheet: Download datasheet 1

Antibodies-Oncology
: AO-03-GB115433-50
: 10 Produits
Hurry! only 10 items left in stock.

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