Anti-URP2/Kindlin-3 Rabbit pAb - 50 µL

Anti-URP2/Kindlin-3 Rabbit pAb - 50 µL

Antibodies-Oncology
AO-03-GB113250-50
  • Specification: 50 µL
  • Applications: WB
  • Species: H,M,R
  • Dilution: 1: 500-1: 1000
  • Positive tissue: liver
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Product Information

Protein full name

Fermitin family homolog 3

Synonyms

FERMT3, KIND3, Kindlin 3, MIG 2, MIG2 like protein, MIG2B, Unc 112 related protein 2, UNC112C, URP2, URP2SF

Uniprot ID

Q8K1B8

Immunogen

Recombinant protein corresponding to Mouse URP2/Kindlin-3

Isotype

IgG

Predicted MW./Observed MW.

76 kDa / 72 kDa

Purity

Affinity purification

Applications

ApplicationsSpeciesDilutionPositive Tissue
WBHuman, Mouse, Rat1: 500-1: 1000liver

Background

Kindlin-3 (FERMT-3) is known to be central in hemostasis and thrombosis control and its deficiency disrupts platelet aggregation and causes Leukocyte Adhesion Deficiency disease. Point mutations in the kindlin-3 gene have been identified in humans with a rare inherited Integrin Activation efficiency Disease (IADD), also designated as Leukocyte Adhesion Deficiency syndrome (LAD-III or LADI variant). Kindlin-3 expression is restricted to cells of hematopoietic origin.

Images

01VaQJ5HxslqULS.jpg

 WB analysis of URP2/Kindlin-3(GB113250).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 1000, 4°C overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.

0247Gr8794MasRE.jpg

 WB analysis of URP2/Kindlin-3(GB113250).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 1000, 4°C overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.

Storage

Storage Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 µg/mL BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

Datasheet: Download datasheet 1

Antibodies-Oncology
: AO-03-GB113250-50
: 10 Produits
Hurry! only 10 items left in stock.

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