Anti-TRAF2 Rabbit pAb - 50 µL
- Specification: 50 µL
- Applications: WB
- Species: H,M,R
- Dilution: 1: 500-1: 1000
- Positive tissue: ovary, testis
Product Information
Protein full name | TNF receptor-associated factor 2 |
Synonyms | Traf2, TRAF2, MGC:45012, TRAP, TRAP3, TNF receptor associated factor 2, RNF117 |
Uniprot ID | P39429 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse TRAF2 |
Isotype | IgG |
Predicted MW./Observed MW. | 56 kDa / 53 kDa |
Purity | Affinity purification |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 500-1: 1000 | ovary, testis |
Background
Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switching from IgM to IgG. Has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. Is an essential constituent of several E3 ubiquitin-protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases.
Images
| WB analysis of TRAF2(GB11891). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 500, 4°C overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h. |
| WB analysis of TRAF2(GB11891). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 500, 4°C overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 µg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
Datasheet: Download datasheet 1
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