Anti-GilZ/TilZ Rabbit pAb - 100 µL

Anti-GilZ/TilZ Rabbit pAb - 100 µL

Antibodies-Oncology
AO-03-GB11303-100
  • Specification: 100 µL
  • Applications: IHC | IF
  • Species: M,R | M,R
  • Dilution: 1:1500-1:3000 | 1:800-1:1600
  • Positive tissue: Testis,brain,lung, kidney,ovary | Testis,brain,lung, kidney,ovary
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Product Information

Protein full name

TSC22 domain family protein 3

Synonyms

TSC22D3, DIP, DSIPI, GILZ, TSC-22R, hDIP, TSC22 domain family member 3

Uniprot ID

Q9Z2S7

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse GILZ

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Applications

ApplicationsSpeciesDilutionPositive Tissue
IHC/IFMouse, Rat1: 800-1: 3000lung, testis, brain

Background

Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities (By similarity).

Images

01gIgJSJSt8dvJf.jpg

 IHC analysis of GilZ/TilZ(GB11303).
Sample: Mouse testis, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98°C, 20 min.
Primary antibody: 1: 1500, 4°C overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

026rrYdmjhgbaD1.jpg

 IHC analysis of GilZ/TilZ(GB11303).
Sample: Rat brain, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98°C, 20 min.
Primary antibody: 1: 1500, 4°C overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

03S35Da3z9BFuhq.jpg

 IHC analysis of GilZ/TilZ(GB11303).
Sample: Rat testis, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98°C, 20 min.
Primary antibody: 1: 1500, 4°C overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

Storage

Storage Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 µg/mL BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

Datasheet: Download datasheet 1

Antibodies-Oncology
: AO-03-GB11303-100
: 10 Produits
Hurry! only 10 items left in stock.

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