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Antibody Product Overview
| ELK.No | ES18367 |
| Product name | AMPL rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 51056 |
| Human Swiss-Prot | P28838 |
| Source | Rabbit |
| Isotype | IgG |
| Target | AMPL |
| Fields | >>Arginine and proline metabolism;>>Glutathione metabolism;>>Metabolic pathways |
| Gene name | LAP3 LAPEP PEPS |
| Protein name | AMPL |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 66988 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9CPY7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 289668 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q68FS4 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human AMPL AA range: 332-382 |
| Specificity | This antibody detects endogenous levels of AMPL at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 57kD |
| Observed band (KD) | |
| Background | |
| Function | catalytic activity:Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.,catalytic activity:Release of N-terminal proline from a peptide.,cofactor:Binds 2 zinc ions per subunit. One zinc ion is tightly bound and essential for enzyme activity, while the second metal coordination site can be occupied by zinc, magnesium or manganese to give enzymes of different activities.,function:Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.,similarity:Belongs to the peptidase M17 family.,subunit:Homohexamer., |
| Subcellular location | Cytoplasm . |
| Expression |
Additional Images
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Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18367-50
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