AMPL rabbit pAb

AMPL rabbit pAb

AO-06-ES18367-50

AMPL rabbit pAb 50μL

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Antibody Product Overview

ELK.NoES18367
Product nameAMPL rabbit pAb
ReactivityHuman; Mouse;Rat
ApplicationsWB
Other name
Size50μL
Unit price ($)148
Human gene ID51056
Human Swiss-ProtP28838
SourceRabbit
IsotypeIgG
TargetAMPL
Fields>>Arginine and proline metabolism;>>Glutathione metabolism;>>Metabolic pathways
Gene nameLAP3 LAPEP PEPS
Protein nameAMPL
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID66988
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ9CPY7
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID289668
Rat gene linkView Rat Gene
Rat Swiss-ProtQ68FS4
Rat Swiss linkView Rat Swiss-Prot
ImmunogenSynthesized peptide derived from human AMPL AA range: 332-382
SpecificityThis antibody detects endogenous levels of AMPL at Human/Mouse/Rat
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)57kD
Observed band (KD)
Background
Functioncatalytic activity:Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.,catalytic activity:Release of N-terminal proline from a peptide.,cofactor:Binds 2 zinc ions per subunit. One zinc ion is tightly bound and essential for enzyme activity, while the second metal coordination site can be occupied by zinc, magnesium or manganese to give enzymes of different activities.,function:Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.,similarity:Belongs to the peptidase M17 family.,subunit:Homohexamer.,
Subcellular locationCytoplasm .
Expression

Additional Images

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Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18367-50
: 10 Produits
Hurry! only 10 items left in stock.

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