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Antibody Product Overview
| ELK.No | ES6395 |
| Product name | NMBR rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IF;ELISA |
| Other name | NMBR; Neuromedin-B receptor; NMB-R; Epididymis tissue protein Li 185a; Neuromedin-B-preferring bombesin receptor |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 4829 |
| Human Swiss-Prot | P28336 |
| Source | Rabbit |
| Isotype | IgG |
| Target | NMBR |
| Fields | >>Neuroactive ligand-receptor interaction |
| Gene name | NMBR |
| Protein name | Neuromedin-B receptor |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 18101 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O54799 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25264 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P24053 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NMBR. AA range:221-270 |
| Specificity | NMBR Polyclonal Antibody detects endogenous levels of NMBR protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 43kD |
| Background | This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016], |
| Function | function:Receptor for neuromedin-B.,similarity:Belongs to the G-protein coupled receptor 1 family., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Expressed in epididymis (at protein level). |
Additional Images
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Western Blot analysis of 293 cells using NMBR Polyclonal Antibody
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Immunofluorescence analysis of A549 cells, using NMBR Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from 293 and Jurkat cells, using NMBR Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of 1) Human Brain Tissue, 2) Rat Brain Tissue using NMBR Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
: AO-06-ES6395-100
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