Français
English
Antibody Product Overview
| ELK.No | ES6395 |
| Product name | NMBR rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IF;ELISA |
| Other name | NMBR; Neuromedin-B receptor; NMB-R; Epididymis tissue protein Li 185a; Neuromedin-B-preferring bombesin receptor |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 4829 |
| Human Swiss-Prot | P28336 |
| Source | Rabbit |
| Isotype | IgG |
| Target | NMBR |
| Fields | >>Neuroactive ligand-receptor interaction |
| Gene name | NMBR |
| Protein name | Neuromedin-B receptor |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 18101 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | O54799 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25264 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P24053 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NMBR. AA range:221-270 |
| Specificity | NMBR Polyclonal Antibody detects endogenous levels of NMBR protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 43kD |
| Background | This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016], |
| Function | function:Receptor for neuromedin-B.,similarity:Belongs to the G-protein coupled receptor 1 family., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Expressed in epididymis (at protein level). |
Additional Images
No image
Western Blot analysis of 293 cells using NMBR Polyclonal Antibody
No image
Immunofluorescence analysis of A549 cells, using NMBR Antibody. The picture on the right is blocked with the synthesized peptide.
No image
Western blot analysis of lysates from 293 and Jurkat cells, using NMBR Antibody. The lane on the right is blocked with the synthesized peptide.
No image
Western blot analysis of 1) Human Brain Tissue, 2) Rat Brain Tissue using NMBR Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
: AO-06-ES6395-100
: 10 Produits
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package