Anti-Bax Mouse mAb, Primary Antibody
Ref: AO-03-GB12690
Volume: 10, 25, 50 and 100 µl
|
Protein full name |
Apoptosis regulator BAX |
|
Synonyms |
BAX, BCL2L4, BCL2 associated X protein, BCL2 associated X, apoptosis regulator |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Bax |
|
Uniprot ID |
Q07813 |
|
Isotype |
IgG1,κ |
|
Purity |
Affinity purification |
|
Predicted MW. / Observed MW. |
21 kDa / 21 kDa |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
liver, lung, kidney |
Background
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein.
Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Images
|
|
Western blot analysis of Bax (AO-03-GB12690) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
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